Drawing on nearly four decades at the National Cancer Institute, Dr. Francis W. Ruscetti offers an insider’s view of the scientific controversies shaping modern medicine. Readers follow his journey from isolating the first pathogenic human retrovirus to pioneering HIV-AIDS research.

Through firsthand accounts of laboratory discoveries and policy debates, this book reveals how political and financial agendas can influence public health outcomes. Ruscetti examines critical moments in immune system research, the emergence of chronic disease investigations, and the recent COVID-19 pandemic.

Rich with behind-the-scenes anecdotes, the narrative questions whether government science always serves the common good or if hidden interests drive key decisions.

Readers will gain:

• Historical context on retrovirology and immune system breakthroughs
• Firsthand lab insights from a founding retrovirologist
• Analysis of transparency challenges in government science

Ending Plague offers a rigorous yet accessible exploration of how scientific truths emerge and the forces that shape them.

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